Flight TW841 (Tel Aviv-Athens-Rome-New York) left Athens at 09:12 GMT for a 1 hour and 48 minute flight to Rome. The flight was cruising at FL280 when to suddenly enter a steep climb attitude. The captain of PanAm flight 110 who witnessed the event, said the aircraft then rolled to the left into a steep descent. The Boeing 707 disintegrated and crashed into the sea. It was determined that the detonation of an explosive device in the aft cargo compartment buckled and damaged the cabin floor in such a manner that one or more of the elevator and rudder system control cables was stretched and, perhaps, broken. The resultant displacement of control surfaces caused a violent pitch up and yaw and made the aircraft uncontrollable. PROBABLE CAUSE: “The detonation of an explosive device within the aft cargo compartment of the aircraft which rendered the aircraft uncontrollable”.