An aircraft incident occurred during a non-scheduled flight from Mooseonee to Nemiscan Settlement. The pilot utilized rear fuel tanks, containing approximately 150 gallons of fuel, with 10-15 gallons in each tank. Power settings were 28 inches manifold pressure and 2050 rpm with automatic lean mixture. Approximately 50 minutes after takeoff, left engine fuel pressure dropped to zero, and the engine failed. The booster pumps were switched on, and tank selections were changed without affecting the engine. Right engine fuel pressure dropped to zero, and the engine failed. The aircraft was forced into trees 1000 ft from the Rupert River, resulting in a severe landing. Examination of the wreckage revealed the front fuel tanks were empty, with no fuel used from either tank. The probable cause is engine failure due to fuel exhaustion.An aircraft incident occurred during a non-scheduled flight from Mooseonee to Nemiscan Settlement. The pilot utilized rear fuel tanks, containing approximately 150 gallons of fuel, with 10-15 gallons in each tank. Power settings were 28 inches manifold pressure and 2050 rpm with automatic lean mixture. Approximately 50 minutes after takeoff, left engine fuel pressure dropped to zero, and the engine failed. The booster pumps were switched on, and tank selections were changed without affecting the engine. Right engine fuel pressure dropped to zero, and the engine failed. The aircraft was forced into trees 1000 ft from the Rupert River, resulting in a severe landing. Examination of the wreckage revealed the front fuel tanks were empty, with no fuel used from either tank. The probable cause is engine failure due to fuel exhaustion.